Innovating healthcare, producing human tissues by 3D positioning of cells
With the discovery of iPS cells (induced pluripotent stem cells), which differentiate into many different types of cells, eyes of the world are on regenerative medicine—restoring physical functions lost due to disease and injury.
The technology to build three-dimensional biological tissue from iPS cells also goes beyond regenerative medicine. Research and development efforts are being accelerated, at the prospects for its application to finding causes of diseases, developing new pharmaceuticals, and testing the safety and toxicity of drugs and cosmetics.
To reproduce biological tissue structures that are close to those of living bodies, you need to appropriately arrange different types of cells and assemble them three-dimensionally.
Research and development of 3D bioprinters is under way at Ricoh. This technology uses an original inkjet system, which can arrange cells very precisely. It will lead to the production of artificial human tissues that are very close to those of living bodies.
The vision of Ricoh is to be innovation leader in healthcare by providing functional tissues and organs using our bioprinting for organ replacement and drug discovery.
*This research was partially supported by Japan Agency for Medical Research and Development (AMED)
(Exhibition) nano tech 2016, the 15th International Nanotechnology Exhibition & Conference
”Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity by RNA-seq analysis” Scientific Reports volume 10, Article number: 7158 (2020) （Scientific Reports Web site）